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KMID : 0388220130200010056
Journal of the Korean Rheumatism Association
2013 Volume.20 No. 1 p.56 ~ p.58
Myoclonus as an Anticipatory Symptom of Diffuse Central Nervous System Involvement in Neuropsychiatric Systemic Lupus Erythematosus
Lee Min-Jin

Lee Ko-Eun
Lee Ji-Soo
Abstract
The clinical manifestations of nervous system involvement in systemic lupus erythematosus (SLE) are highly diverse and their pathogenic mechanisms are incompletely understood. Neuropsychiatric SLE (NPSLE) poses difficulty in making the proper diagnosis, especially in circumstances where its initial symptoms are diffuse neuropsychiatric symptoms. We describe a 43-year old woman who exhibited a myoclonic jerk of the abdominal wall, followed shortly by acute confusion, which was attributed to SLE. Therapy with high dose corticosteroids completely reversed the symptoms. Myoclonus can be an anticipatory symptom of diffuse neurologic dysfunction in patients with NPSLE.
KEYWORD
NPSLE, Diffuse neuropsychiatric symptoms, Myoclonus
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